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Allopurinol Therapy in Gout Patients Does Not Associate with Beneficial Cardiovascular Outcomes: A Population-Based Matched-Cohort Study

INTRODUCTION: Previous studies have shown an association between gout and/or hyperuricemia and a subsequent increase in cardiovascular disease (CVD) outcomes. Allopurinol reduces vascular oxidative stress, ameliorates inflammatory state, improves endothelial function, and prevents atherosclerosis pr...

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Detalles Bibliográficos
Autores principales: Kok, Victor C., Horng, Jorng-Tzong, Chang, Wan-Shan, Hong, Ya-Fang, Chang, Tzu-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045898/
https://www.ncbi.nlm.nih.gov/pubmed/24897240
http://dx.doi.org/10.1371/journal.pone.0099102

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