Cargando…

iDrug: a web-accessible and interactive drug discovery and design platform

BACKGROUND: The progress in computer-aided drug design (CADD) approaches over the past decades accelerated the early-stage pharmaceutical research. Many powerful standalone tools for CADD have been developed in academia. As programs are developed by various research groups, a consistent user-friendl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xia, Chen, Haipeng, Yang, Feng, Gong, Jiayu, Li, Shiliang, Pei, Jianfeng, Liu, Xiaofeng, Jiang, Hualiang, Lai, Luhua, Li, Honglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046018/ https://www.ncbi.nlm.nih.gov/pubmed/24955134 http://dx.doi.org/10.1186/1758-2946-6-28

Ejemplares similares

iDrug: Integration of drug repositioning and drug-target prediction via cross-network embedding
por: Chen, Huiyuan, et al.
Publicado: (2020)

PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database
por: Wang, Xia, et al.
Publicado: (2017)

RD-Metabolizer: an integrated and reaction types extensive approach to predict metabolic sites and metabolites of drug-like molecules
por: Meng, Jiajia, et al.
Publicado: (2017)

PDTD: a web-accessible protein database for drug target identification
por: Gao, Zhenting, et al.
Publicado: (2008)

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach
por: Liu, Xiaofeng, et al.
Publicado: (2010)

Computational methods for drug design and discovery: focus on China
por: Zheng, Mingyue, et al.
Publicado: (2013)

Individualized versus standardized risk assessment in patients at high risk for adverse drug reactions (IDrug) – study protocol for a pragmatic randomized controlled trial
por: Stingl, Julia Carolin, et al.
Publicado: (2016)

Real-time GIS data model and sensor web service platform for environmental data management
por: Gong, Jianya, et al.
Publicado: (2015)

Cyndi: a multi-objective evolution algorithm based method for bioactive molecular conformational generation
por: Liu, Xiaofeng, et al.
Publicado: (2009)

Structure-based de novo drug design using 3D deep generative models
por: Li, Yibo, et al.
Publicado: (2021)

Individualized versus Standardized Risk Assessment in Patients at High Risk for Adverse Drug Reactions (The IDrug Randomized Controlled Trial)–Never Change a Running System?
por: Just, Katja S., et al.
Publicado: (2021)

Bioactive conformational generation of small molecules: A comparative analysis between force-field and multiple empirical criteria based methods
por: Bai, Fang, et al.
Publicado: (2010)

An improved sequence based prediction protocol for DNA-binding proteins using SVM and comprehensive feature analysis
por: Zou, Chuanxin, et al.
Publicado: (2013)

TaxKB: a knowledge base for new taxane-related drug discovery
por: Murugan, Kasi, et al.
Publicado: (2015)

Comprehensive ensemble in QSAR prediction for drug discovery
por: Kwon, Sunyoung, et al.
Publicado: (2019)

A phenomics approach for antiviral drug discovery
por: Rietdijk, Jonne, et al.
Publicado: (2021)

LigBuilder V3: A Multi-Target de novo Drug Design Approach
por: Yuan, Yaxia, et al.
Publicado: (2020)

Discovery: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria
por: Joubert, Fourie, et al.
Publicado: (2009)

Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery
por: Zhan, Yanai, et al.
Publicado: (2015)

Application of the automated haematology analyzer XN-30 for discovery and development of anti-malarial drugs
por: Tougan, Takahiro, et al.
Publicado: (2019)

An effective docking strategy for virtual screening based on multi-objective optimization algorithm
por: Li, Honglin, et al.
Publicado: (2009)

Prediction of Drug-Likeness Using Deep Autoencoder Neural Networks
por: Hu, Qiwan, et al.
Publicado: (2018)

A Biosynthetic Platform for Antimalarial Drug Discovery
por: Wilkinson, Mark D., et al.
Publicado: (2020)

Discovery-2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria
por: Mpangase, Phelelani T, et al.
Publicado: (2013)

ChEMBL web services: streamlining access to drug discovery data and utilities
por: Davies, Mark, et al.
Publicado: (2015)

A combined computational and experimental strategy identifies mutations conferring resistance to drugs targeting the BCR-ABL fusion protein
por: Liu, Jinxin, et al.
Publicado: (2020)

Towards agile large-scale predictive modelling in drug discovery with flow-based programming design principles
por: Lampa, Samuel, et al.
Publicado: (2016)

ksRepo: a generalized platform for computational drug repositioning
por: Brown, Adam S., et al.
Publicado: (2016)

Polyphony: superposition independent methods for ensemble-based drug discovery
por: Pitt, William R, et al.
Publicado: (2014)

Synergistic and Antagonistic Drug Combinations Depend on Network Topology
por: Yin, Ning, et al.
Publicado: (2014)

SPIEDw: a searchable platform-independent expression database web tool
por: Williams, Gareth
Publicado: (2013)

DRAP: a toolbox for drug response analysis and visualization tailored for preclinical drug testing on patient-derived xenograft models
por: Li, Quanxue, et al.
Publicado: (2019)

High-content live cell imaging with RNA probes: advancements in high-throughput antimalarial drug discovery
por: Cervantes, Serena, et al.
Publicado: (2009)

Drug use trajectory patterns among older drug users
por: Boeri, Miriam, et al.
Publicado: (2011)

TarFisDock: a web server for identifying drug targets with docking approach
por: Li, Honglin, et al.
Publicado: (2006)

An omics perspective on drug target discovery platforms
por: Paananen, Jussi, et al.
Publicado: (2019)

Levoglucosenone: Bio-Based Platform for Drug Discovery
por: Camp, Jason E., et al.
Publicado: (2022)

XMPP for cloud computing in bioinformatics supporting discovery and invocation of asynchronous web services
por: Wagener, Johannes, et al.
Publicado: (2009)

PLATO: A Predictive Drug Discovery Web Platform for Efficient Target Fishing and Bioactivity Profiling of Small Molecules
por: Ciriaco, Fulvio, et al.
Publicado: (2022)

A multi-modal relative spatial access assessment approach to measure spatial accessibility to primary care providers
por: Lin, Yan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_i83c5galh47lt9uhva6pcdpers