Thyroid nodules in childhood: indications for biopsy and surgery

Aims of this commentary is to report the most recent views about epidemiology, diagnostic procedures, malignancy risk factors and clinical management of thyroid nodules in children. On the basis of our personal experiences and recent literature evidences, we conclude that: a) if nodule is accompanie...

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Autores principales: De Luca, Filippo, Aversa, Tommaso, Alessi, Luca, Cama, Valeria, Costanzo, Daria, Genovese, Cristina, Scuderi, Veronica, Vadalà, Roberta, Zoccali, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046031/
https://www.ncbi.nlm.nih.gov/pubmed/24887308
http://dx.doi.org/10.1186/1824-7288-40-48
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author De Luca, Filippo
Aversa, Tommaso
Alessi, Luca
Cama, Valeria
Costanzo, Daria
Genovese, Cristina
Scuderi, Veronica
Vadalà, Roberta
Zoccali, Giuseppe
author_facet De Luca, Filippo
Aversa, Tommaso
Alessi, Luca
Cama, Valeria
Costanzo, Daria
Genovese, Cristina
Scuderi, Veronica
Vadalà, Roberta
Zoccali, Giuseppe
author_sort De Luca, Filippo
collection PubMed
description Aims of this commentary is to report the most recent views about epidemiology, diagnostic procedures, malignancy risk factors and clinical management of thyroid nodules in children. On the basis of our personal experiences and recent literature evidences, we conclude that: a) if nodule is accompanied by lymphadenopathy and/or other alert findings, fine-needle aspiration biopsy (FNAB) should be recommended; b) if no lymphadenopathy and no other clinical and ultrasonographic alert signs are observed, work-up can progress to FNAB only if nodule persists or grows over time, even under levo-thyroxine therapy.
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spelling pubmed-40460312014-06-06 Thyroid nodules in childhood: indications for biopsy and surgery De Luca, Filippo Aversa, Tommaso Alessi, Luca Cama, Valeria Costanzo, Daria Genovese, Cristina Scuderi, Veronica Vadalà, Roberta Zoccali, Giuseppe Ital J Pediatr Commentary Aims of this commentary is to report the most recent views about epidemiology, diagnostic procedures, malignancy risk factors and clinical management of thyroid nodules in children. On the basis of our personal experiences and recent literature evidences, we conclude that: a) if nodule is accompanied by lymphadenopathy and/or other alert findings, fine-needle aspiration biopsy (FNAB) should be recommended; b) if no lymphadenopathy and no other clinical and ultrasonographic alert signs are observed, work-up can progress to FNAB only if nodule persists or grows over time, even under levo-thyroxine therapy. BioMed Central 2014-05-19 /pmc/articles/PMC4046031/ /pubmed/24887308 http://dx.doi.org/10.1186/1824-7288-40-48 Text en Copyright © 2014 De Luca et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
De Luca, Filippo
Aversa, Tommaso
Alessi, Luca
Cama, Valeria
Costanzo, Daria
Genovese, Cristina
Scuderi, Veronica
Vadalà, Roberta
Zoccali, Giuseppe
Thyroid nodules in childhood: indications for biopsy and surgery
title Thyroid nodules in childhood: indications for biopsy and surgery
title_full Thyroid nodules in childhood: indications for biopsy and surgery
title_fullStr Thyroid nodules in childhood: indications for biopsy and surgery
title_full_unstemmed Thyroid nodules in childhood: indications for biopsy and surgery
title_short Thyroid nodules in childhood: indications for biopsy and surgery
title_sort thyroid nodules in childhood: indications for biopsy and surgery
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046031/
https://www.ncbi.nlm.nih.gov/pubmed/24887308
http://dx.doi.org/10.1186/1824-7288-40-48
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