Cargando…
Restrictive vs Liberal Blood Transfusion for Acute Upper Gastrointestinal Bleeding: Rationale and Protocol for a Cluster Randomized Feasibility Trial
Acute upper gastrointestinal bleeding (AUGIB) is the commonest reason for hospitalization with hemorrhage in the UK and the leading indication for transfusion of red blood cells (RBCs). Observational studies suggest an association between more liberal RBC transfusion and adverse patient outcomes, an...
Autores principales: | Jairath, Vipul, Kahan, Brennan C., Gray, Alasdair, Doré, Caroline J., Mora, Ana, Dyer, Claire, Stokes, Elizabeth A., Llewelyn, Charlotte, Bailey, Adam A., Dallal, Helen, Everett, Simon M., James, Martin W., Stanley, Adrian J., Church, Nicholas, Darwent, Melanie, Greenaway, John, Le Jeune, Ivan, Reckless, Ian, Campbell, Helen E., Meredith, Sarah, Palmer, Kelvin R., Logan, Richard F.A., Travis, Simon P.L., Walsh, Timothy S., Murphy, Michael F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Grune And Stratton
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046243/ https://www.ncbi.nlm.nih.gov/pubmed/23706959 http://dx.doi.org/10.1016/j.tmrv.2013.04.001 |
Ejemplares similares
-
Update on the transfusion in gastrointestinal bleeding (TRIGGER) trial: statistical analysis plan for a cluster-randomised feasibility trial
por: Kahan, Brennan C, et al.
Publicado: (2013) -
Costs and quality of life associated with acute upper gastrointestinal bleeding in the UK: cohort analysis of patients in a cluster randomised trial
por: Campbell, H E, et al.
Publicado: (2015) -
The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies
por: Kahan, Brennan C, et al.
Publicado: (2014) -
Can we reduce bias in open-label trials when blinded outcome assessment is not possible? An example from the trigger trial
por: Kahan, Brennan, et al.
Publicado: (2015) -
Outcome pre-specification requires sufficient detail to guard against outcome switching in clinical trials: a case study
por: Kahan, Brennan C., et al.
Publicado: (2018)