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Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis
Red man syndrome (RMS) has frequently been reported to occur with intravenous vancomycin therapy. However, there have been few reports of this complication during intraperitoneal (IP) treatment with vancomycin. This report describes an 11-year-old boy with end stage renal disease who developed RMS 4...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046263/ https://www.ncbi.nlm.nih.gov/pubmed/24926475 http://dx.doi.org/10.3389/fped.2014.00055 |
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author | Domis, Melissa J. Moritz, Michael L. |
author_facet | Domis, Melissa J. Moritz, Michael L. |
author_sort | Domis, Melissa J. |
collection | PubMed |
description | Red man syndrome (RMS) has frequently been reported to occur with intravenous vancomycin therapy. However, there have been few reports of this complication during intraperitoneal (IP) treatment with vancomycin. This report describes an 11-year-old boy with end stage renal disease who developed RMS 45 min into the initial loading dose of IP vancomycin for the treatment of bacterial peritonitis with a vancomycin level of 38.8 mcg/mL. The patient developed this adverse reaction despite appropriate initial loading dose per ISPD guidelines for continuous treatment (1000 mg/L). This case emphasizes the importance of monitoring for adverse reactions of vancomycin therapy, and raises dosing considerations that differ slightly from the currently recommended ISPD guidelines for IP vancomycin treatment in the treatment of bacterial peritonitis. |
format | Online Article Text |
id | pubmed-4046263 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-40462632014-06-12 Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis Domis, Melissa J. Moritz, Michael L. Front Pediatr Pediatrics Red man syndrome (RMS) has frequently been reported to occur with intravenous vancomycin therapy. However, there have been few reports of this complication during intraperitoneal (IP) treatment with vancomycin. This report describes an 11-year-old boy with end stage renal disease who developed RMS 45 min into the initial loading dose of IP vancomycin for the treatment of bacterial peritonitis with a vancomycin level of 38.8 mcg/mL. The patient developed this adverse reaction despite appropriate initial loading dose per ISPD guidelines for continuous treatment (1000 mg/L). This case emphasizes the importance of monitoring for adverse reactions of vancomycin therapy, and raises dosing considerations that differ slightly from the currently recommended ISPD guidelines for IP vancomycin treatment in the treatment of bacterial peritonitis. Frontiers Media S.A. 2014-06-05 /pmc/articles/PMC4046263/ /pubmed/24926475 http://dx.doi.org/10.3389/fped.2014.00055 Text en Copyright © 2014 Domis and Moritz. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Domis, Melissa J. Moritz, Michael L. Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis |
title | Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis |
title_full | Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis |
title_fullStr | Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis |
title_full_unstemmed | Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis |
title_short | Red Man Syndrome Following Intraperitoneal Vancomycin in a Child with Peritonitis |
title_sort | red man syndrome following intraperitoneal vancomycin in a child with peritonitis |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046263/ https://www.ncbi.nlm.nih.gov/pubmed/24926475 http://dx.doi.org/10.3389/fped.2014.00055 |
work_keys_str_mv | AT domismelissaj redmansyndromefollowingintraperitonealvancomycininachildwithperitonitis AT moritzmichaell redmansyndromefollowingintraperitonealvancomycininachildwithperitonitis |