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Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

Multidrug ATP binding cassette (ABC) exporters are ubiquitous ABC transporters that extrude cytotoxic molecules across cell membranes. Despite recent progress in structure determination of these transporters, the conformational motion that transduces the energy of ATP hydrolysis to the work of subst...

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Detalles Bibliográficos
Autores principales:	Mishra, Smriti, Verhalen, Brandy, Stein, Richard A, Wen, Po-Chao, Tajkhorshid, Emad, Mchaourab, Hassane S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046567/ https://www.ncbi.nlm.nih.gov/pubmed/24837547 http://dx.doi.org/10.7554/eLife.02740

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