T cell-intrinsic role of IL-6 signaling in primary and memory responses

Innate immune recognition is critical for the induction of adaptive immune responses; however the underlying mechanisms remain incompletely understood. In this study, we demonstrate that T cell-specific deletion of the IL-6 receptor α chain (IL-6Rα) results in impaired Th1 and Th17 T cell responses...

Descripción completa

Detalles Bibliográficos
Autores principales: Nish, Simone A, Schenten, Dominik, Wunderlich, F Thomas, Pope, Scott D, Gao, Yan, Hoshi, Namiko, Yu, Shuang, Yan, Xiting, Lee, Heung Kyu, Pasman, Lesley, Brodsky, Igor, Yordy, Brian, Zhao, Hongyu, Brüning, Jens, Medzhitov, Ruslan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046568/
https://www.ncbi.nlm.nih.gov/pubmed/24842874
http://dx.doi.org/10.7554/eLife.01949

Ejemplares similares

Ejemplares similares