MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies

BACKGROUND: The progression of Alzheimer’s disease (AD) is associated with an increase of phosphorylated tau in the brain. One of the earliest phosphorylated sites on tau is Ser(262) that is preferentially phosphorylated by microtubule affinity regulating kinase (MARK), of which four isoforms exist....

Descripción completa

Detalles Bibliográficos
Autores principales: Lund, Harald, Gustafsson, Elin, Svensson, Anne, Nilsson, Maria, Berg, Margareta, Sunnemark, Dan, von Euler, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046661/
https://www.ncbi.nlm.nih.gov/pubmed/24533944
http://dx.doi.org/10.1186/2051-5960-2-22

Ejemplares similares

Ejemplares similares