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Myositis facilitates preclinical accumulation of pathological prion protein in muscle
BACKGROUND: In human and animal prion diseases, pathological prion protein, PrP(Sc), as well as prion infectivity is mainly found in the central nervous system, but also in lymphoid organs and muscle. Pathophysiology of prion colonization of lymphoid organs has been studied intensively, yet how myos...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046662/ https://www.ncbi.nlm.nih.gov/pubmed/24299111 http://dx.doi.org/10.1186/2051-5960-1-78 |