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Myositis facilitates preclinical accumulation of pathological prion protein in muscle

BACKGROUND: In human and animal prion diseases, pathological prion protein, PrP(Sc), as well as prion infectivity is mainly found in the central nervous system, but also in lymphoid organs and muscle. Pathophysiology of prion colonization of lymphoid organs has been studied intensively, yet how myos...

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Detalles Bibliográficos
Autores principales: Neumann, Melanie, Krasemann, Susanne, Schröck, Katharina, Steinbach, Karin, Glatzel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046662/
https://www.ncbi.nlm.nih.gov/pubmed/24299111
http://dx.doi.org/10.1186/2051-5960-1-78

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