Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

BACKGROUND: Target enrichment and resequencing is a widely used approach for identification of cancer genes and genetic variants associated with diseases. Although cost effective compared to whole genome sequencing, analysis of many samples constitutes a significant cost, which could be reduced by p...

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Detalles Bibliográficos
Autores principales: Berglund, Eva C, Lindqvist, Carl Mårten, Hayat, Shahina, Övernäs, Elin, Henriksson, Niklas, Nordlund, Jessica, Wahlberg, Per, Forestier, Erik, Lönnerholm, Gudmar, Syvänen, Ann-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046713/
https://www.ncbi.nlm.nih.gov/pubmed/24314227
http://dx.doi.org/10.1186/1471-2164-14-856

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