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Kinetic Mechanism at the Branchpoint between the DNA Synthesis and Editing Pathways in Individual DNA Polymerase Complexes

[Image: see text] Exonucleolytic editing of incorrectly incorporated nucleotides by replicative DNA polymerases (DNAPs) plays an essential role in the fidelity of DNA replication. Editing requires that the primer strand of the DNA substrate be transferred between the DNAP polymerase and exonuclease...

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Detalles Bibliográficos
Autores principales:	Lieberman, Kate R., Dahl, Joseph M., Wang, Hongyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046759/ https://www.ncbi.nlm.nih.gov/pubmed/24761828 http://dx.doi.org/10.1021/ja5026408

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