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The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice

BACKGROUND: The deposition of the amyloid β-peptide (Aβ) in the brain is one of the hallmarks of Alzheimer’s disease (AD). It is not yet clear whether Aβ always leads to similar changes or whether it induces different features of neurodegeneration in relation to its intra- and/or extracellular local...

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Detalles Bibliográficos
Autores principales: Rijal Upadhaya, Ajeet, Scheibe, Frederik, Kosterin, Irina, Abramowski, Dorothee, Gerth, Janina, Kumar, Sathish, Liebau, Stefan, Yamaguchi, Haruyasu, Walter, Jochen, Staufenbiel, Matthias, Thal, Dietmar Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046770/
https://www.ncbi.nlm.nih.gov/pubmed/24252227
http://dx.doi.org/10.1186/2051-5960-1-77