Cargando…

Co-delivery of Cisplatin and Rapamycin for Enhanced Anticancer Therapy through Synergistic Effects and Microenvironment Modulation

[Image: see text] The tumor microenvironment plays an important role in the tumor’s progression and metastasis. Therefore, successful alteration of this delicate setting against the tumor’s favor can open a window for therapeutic efficacy. We have developed a modality to bring about treatment-induce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Shutao, Lin, C. Michael, Xu, Zhenghong, Miao, Lei, Wang, Yuhua, Huang, Leaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046782/ https://www.ncbi.nlm.nih.gov/pubmed/24720540 http://dx.doi.org/10.1021/nn5010815

Ejemplares similares

PolyMetformin combines carrier and anticancer activities for in vivo siRNA delivery
por: Zhao, Yi, et al.
Publicado: (2016)

Nanoparticle-Delivered Transforming Growth Factor-β siRNA Enhances Vaccination against Advanced Melanoma by Modifying Tumor Microenvironment
por: Xu, Zhenghong, et al.
Publicado: (2014)

Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer
por: Chen, Yi-Qing, et al.
Publicado: (2021)

Synergistic anticancer activity of cisplatin combined with tannic acid enhances apoptosis in lung cancer through the PERK-ATF4 pathway
por: Zheng, Xiang, et al.
Publicado: (2023)

Rapamycin in lipoproteins for enhanced delivery
por: Cho, Kyung-Hyun
Publicado: (2012)

Laser-assisted delivery enhances topical uptake of the anticancer agent cisplatin
por: Wenande, Emily, et al.
Publicado: (2018)

Preparation, characterization, and Co-delivery of cisplatin and doxorubicin-loaded liposomes to enhance anticancer Activities
por: Bahrami Parsa, Mahdi, et al.
Publicado: (2023)

Enhanced efficacy in drug-resistant cancer cells through synergistic nanoparticle mediated delivery of cisplatin and decitabine
por: Parhizkar, M., et al.
Publicado: (2020)

Graphene Oxide Nanoplatforms to Enhance Cisplatin-Based Drug Delivery in Anticancer Therapy
por: Giusto, Elena, et al.
Publicado: (2022)

Synergistic anticancer effect of combined crocetin and cisplatin on KYSE-150 cells via p53/p21 pathway
por: Li, Sheng, et al.
Publicado: (2017)

Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma
por: Gemmill, R M, et al.
Publicado: (2005)

Plaque‐Targeted Rapamycin Spherical Nucleic Acids for Synergistic Atherosclerosis Treatment
por: Guo, Yuanyuan, et al.
Publicado: (2022)

Modulating the Tumor Microenvironment to Enhance Tumor Nanomedicine Delivery
por: Zhang, Bo, et al.
Publicado: (2017)

Metformin potentiates rapamycin and cisplatin in gastric cancer in mice
por: Yu, Yu, et al.
Publicado: (2015)

Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategies
por: Liu, Yun, et al.
Publicado: (2020)

Co-Delivery of Cisplatin and Gemcitabine via Viscous Nanoemulsion for Potential Synergistic Intravesical Chemotherapy
por: Chen, Ting-Yu, et al.
Publicado: (2020)

Nanodrug Delivery Systems Modulate Tumor Vessels to Increase the Enhanced Permeability and Retention Effect
por: Huang, Dong, et al.
Publicado: (2021)

Co-Delivery Anticancer Drug Nanoparticles for Synergistic Therapy Against Lung Cancer Cells
por: Shen, Yuzhou, et al.
Publicado: (2020)

Combining the mammalian target of rapamycin inhibitor, rapamycin, with resveratrol has a synergistic effect in multiple myeloma
por: Jin, Hong-Guang, et al.
Publicado: (2018)

Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer
por: Liu, Yu-Hsuan, et al.
Publicado: (2023)

The synergistic anticancer effect of cisplatin combined with Oldenlandia diffusa in osteosarcoma MG-63 cell line in vitro
por: Pu, Feifei, et al.
Publicado: (2016)

Berberine and Cisplatin Exhibit Synergistic Anticancer Effects on Osteosarcoma MG-63 Cells by Inhibiting the MAPK Pathway
por: Gao, Xianxian, et al.
Publicado: (2021)

“Shell-Core” Bilayer Nanoparticle as Chemotherapeutic Drug Co-Delivery Platforms Render Synchronized Microenvironment Respond and Enhanced Antitumor Effects
por: Zeng, Jia, et al.
Publicado: (2023)

Emerging Epigenetic‐Based Nanotechnology for Cancer Therapy: Modulating the Tumor Microenvironment
por: Zhang, Jiaxin, et al.
Publicado: (2023)

Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim
por: Park, Hye-Kyung, et al.
Publicado: (2014)

Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIP(L) degradation, Ripoptosome formation and autophagy-mediated apoptosis
por: Shi, Shaoqing, et al.
Publicado: (2015)

Interactions of Analgesics with Cisplatin: Modulation of Anticancer Efficacy and Potential Organ Toxicity
por: El-Sheikh, Azza, et al.
Publicado: (2021)

Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer
por: Pan, Di, et al.
Publicado: (2021)

Glycol Chitosan-Docosahexaenoic Acid Liposomes for Drug Delivery: Synergistic Effect of Doxorubicin-Rapamycin in Drug-Resistant Breast Cancer
por: Kim, Min Woo, et al.
Publicado: (2019)

Effect of combination of rapamycin and cisplatin on human cervical carcinoma Hela cells
por: Han, Lu, et al.
Publicado: (2013)

Rapamycin Perfluorocarbon Nanoparticle Mitigates Cisplatin-Induced Acute Kidney Injury
por: Zhou, Qingyu, et al.
Publicado: (2023)

Anticancer properties of cannabidiol and Δ(9)-tetrahydrocannabinol and synergistic effects with gemcitabine and cisplatin in bladder cancer cell lines
por: Whynot, Erin G., et al.
Publicado: (2023)

Synergistic Effect of 3-Bromopyruvate in Combination with Rapamycin Impacted Neuroblastoma Metabolism by Inhibiting Autophagy
por: Gan, Lei, et al.
Publicado: (2020)

Co-Delivery of Curcumin and Cisplatin to Enhance Cytotoxicity of Cisplatin Using Lipid-Chitosan Hybrid Nanoparticles
por: Khan, Muhammad Muzamil, et al.
Publicado: (2020)

Cisplatin delivery, anticancer and antibacterial properties of Fe/SBA-16/ZIF-8 nanocomposite
por: Balasamy, Rabindran Jermy, et al.
Publicado: (2019)

Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01
por: Kimura, Kotohiko, et al.
Publicado: (2016)

Mangiferin Ameliorates Cisplatin Induced Acute Kidney Injury by Upregulating Nrf-2 via the Activation of PI3K and Exhibits Synergistic Anticancer Activity With Cisplatin
por: Sadhukhan, Pritam, et al.
Publicado: (2018)

Tumor Microenvironment-Responsive Nanomaterials as Targeted Delivery Carriers for Photodynamic Anticancer Therapy
por: Liu, Houhe, et al.
Publicado: (2020)

Selective synergistic anticancer effects of cisplatin and oridonin against human p53-mutant esophageal squamous carcinoma cells
por: Yang, Huiyu, et al.
Publicado: (2021)

Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma
por: Hou, Lin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l4hc205d8lfj31p7992ul4fs8j