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Tunable Protease-Activatable Virus Nanonodes

[Image: see text] We explored the unique signal integration properties of the self-assembling 60-mer protein capsid of adeno-associated virus (AAV), a clinically proven human gene therapy vector, by engineering proteolytic regulation of virus–receptor interactions such that processing of the capsid...

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Detalles Bibliográficos
Autores principales:	Judd, Justin, Ho, Michelle L., Tiwari, Abhinav, Gomez, Eric J., Dempsey, Christopher, Van Vliet, Kim, Igoshin, Oleg A., Silberg, Jonathan J., Agbandje-McKenna, Mavis, Suh, Junghae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046807/ https://www.ncbi.nlm.nih.gov/pubmed/24796495 http://dx.doi.org/10.1021/nn500550q

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