The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi’s sarcoma associated herpesvirus reactivation

BACKGROUND: SUMOylation, as part of the epigenetic regulation of transcription, has been intensively studied in lower eukaryotes that contain only a single SUMO protein; however, the functions of SUMOylation during mammalian epigenetic transcriptional regulation are largely uncharacterized. Mammals...

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Detalles Bibliográficos
Autores principales: Chang, Pei-Ching, Cheng, Chia-Yang, Campbell, Mel, Yang, Yi-Cheng, Hsu, Hung-Wei, Chang, Ting-Yu, Chu, Chia-Han, Lee, Yi-Wei, Hung, Chiu-Lien, Lai, Shi-Mei, Tepper, Clifford G, Hsieh, Wen-Ping, Wang, Hsei-Wei, Tang, Chuan-Yi, Wang, Wen-Ching, Kung, Hsing-Jien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046822/
https://www.ncbi.nlm.nih.gov/pubmed/24267727
http://dx.doi.org/10.1186/1471-2164-14-824

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