Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo

Homologous recombination (HR) is critical for the repair of double strand breaks and broken replication forks. Although HR is mostly error free, inherent or environmental conditions that either suppress or induce HR cause genomic instability. Despite its importance in carcinogenesis, due to limitati...

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Detalles Bibliográficos
Autores principales: Sukup-Jackson, Michelle R., Kiraly, Orsolya, Kay, Jennifer E., Na, Li, Rowland, Elizabeth A., Winther, Kelly E., Chow, Danielle N., Kimoto, Takafumi, Matsuguchi, Tetsuya, Jonnalagadda, Vidya S., Maklakova, Vilena I., Singh, Vijay R., Wadduwage, Dushan N., Rajapakse, Jagath, So, Peter T. C., Collier, Lara S., Engelward, Bevin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046920/
https://www.ncbi.nlm.nih.gov/pubmed/24901438
http://dx.doi.org/10.1371/journal.pgen.1004299

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