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Cytokine Production but Lack of Proliferation in Peripheral Blood Mononuclear Cells from Chronic Chagas' Disease Cardiomyopathy Patients in Response to T. cruzi Ribosomal P Proteins

BACKGROUND: Trypanosoma cruzi ribosomal P proteins, P2β and P0, induce high levels of antibodies in patients with chronic Chagas' disease Cardiomyopathy (CCC). It is well known that these antibodies alter the beating rate of cardiomyocytes and provoke apoptosis by their interaction with β1-adre...

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Detalles Bibliográficos
Autores principales: Longhi, Silvia A., Atienza, Augusto, Perez Prados, Graciela, Buying, Alcinette, Balouz, Virginia, Buscaglia, Carlos A., Santos, Radleigh, Tasso, Laura M., Bonato, Ricardo, Chiale, Pablo, Pinilla, Clemencia, Judkowski, Valeria A., Gómez, Karina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046937/
https://www.ncbi.nlm.nih.gov/pubmed/24901991
http://dx.doi.org/10.1371/journal.pntd.0002906