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Stage-Dependent Expression and Up-Regulation of Trypanothione Synthetase in Amphotericin B Resistant Leishmania donovani

Kinetoplastids differ from other organisms in their ability to conjugate glutathione and spermidine to form trypanothione which is involved in maintaining redox homeostasis and removal of toxic metabolites. It is also involved in drug resistance, antioxidant mechanism, and defense against cellular o...

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Detalles Bibliográficos
Autores principales:	Equbal, Asif, Suman, Shashi Shekhar, Anwar, Shadab, Singh, Krishn Pratap, Zaidi, Amir, Sardar, Abul Hasan, Das, Pradeep, Ali, Vahab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046939/ https://www.ncbi.nlm.nih.gov/pubmed/24901644 http://dx.doi.org/10.1371/journal.pone.0097600

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