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Targeting Echinococcus multilocularis Stem Cells by Inhibition of the Polo-Like Kinase EmPlk1

BACKGROUND: Alveolar echinococcosis (AE) is a life-threatening disease caused by larvae of the fox-tapeworm Echinococcus multilocularis. Crucial to AE pathology is continuous infiltrative growth of the parasite's metacestode stage, which is driven by a population of somatic stem cells, called g...

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Detalles Bibliográficos
Autores principales: Schubert, Andreas, Koziol, Uriel, Cailliau, Katia, Vanderstraete, Mathieu, Dissous, Colette, Brehm, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046951/
https://www.ncbi.nlm.nih.gov/pubmed/24901228
http://dx.doi.org/10.1371/journal.pntd.0002870