A Protein-Conjugate Approach to Develop a Monoclonal Antibody-Based Antigen Detection Test for the Diagnosis of Human Brucellosis

Human brucellosis is most commonly diagnosed by serology based on agglutination of fixed Brucella abortus as antigen. Nucleic acid amplification techniques have not proven capable of reproducibly and sensitively demonstrating the presence of Brucella DNA in clinical specimens. We sought to optimize...

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Detalles Bibliográficos
Autores principales: Patra, Kailash P., Saito, Mayuko, Atluri, Vidya L., Rolán, Hortensia G., Young, Briana, Kerrinnes, Tobias, Smits, Henk, Ricaldi, Jessica N., Gotuzzo, Eduardo, Gilman, Robert H., Tsolis, Renee M., Vinetz, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046965/
https://www.ncbi.nlm.nih.gov/pubmed/24901521
http://dx.doi.org/10.1371/journal.pntd.0002926

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