Cargando…
Genetic Background Drives Transcriptional Variation in Human Induced Pluripotent Stem Cells
Human iPS cells have been generated using a diverse range of tissues from a variety of donors using different reprogramming vectors. However, these cell lines are heterogeneous, which presents a limitation for their use in disease modeling and personalized medicine. To explore the basis of this hete...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046971/ https://www.ncbi.nlm.nih.gov/pubmed/24901476 http://dx.doi.org/10.1371/journal.pgen.1004432 |