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Identification of Divergent Protein Domains by Combining HMM-HMM Comparisons and Co-Occurrence Detection
Identification of protein domains is a key step for understanding protein function. Hidden Markov Models (HMMs) have proved to be a powerful tool for this task. The Pfam database notably provides a large collection of HMMs which are widely used for the annotation of proteins in sequenced organisms....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046975/ https://www.ncbi.nlm.nih.gov/pubmed/24901648 http://dx.doi.org/10.1371/journal.pone.0095275 |