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NMR Characterization of the Interaction of the Endonuclease Domain of MutL with Divalent Metal Ions and ATP
MutL is a multi-domain protein comprising an N-terminal ATPase domain (NTD) and C-terminal dimerization domain (CTD), connected with flexible linker regions, that plays a key role in DNA mismatch repair. To expand understanding of the regulation mechanism underlying MutL endonuclease activity, our N...
Autores principales: | Mizushima, Ryota, Kim, Ju Yaen, Suetake, Isao, Tanaka, Hiroaki, Takai, Tomoyo, Kamiya, Narutoshi, Takano, Yu, Mishima, Yuichi, Tajima, Shoji, Goto, Yuji, Fukui, Kenji, Lee, Young-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047009/ https://www.ncbi.nlm.nih.gov/pubmed/24901533 http://dx.doi.org/10.1371/journal.pone.0098554 |
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