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Glabridin Mediate Caspases Activation and Induces Apoptosis through JNK1/2 and p38 MAPK Pathway in Human Promyelocytic Leukemia Cells

BACKGROUND: Glabridin, a prenylated isoflavonoid of G. glabra L. roots, has been associated with a wide range of biological properties such as regulation of energy metabolism, estrogenic, neuroprotective, anti-osteoporotic, and skin-whitening in previous studies. However, the effect of glabridin on...

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Detalles Bibliográficos
Autores principales: Huang, Hsin-Lien, Hsieh, Ming-Ju, Chien, Ming-Hsien, Chen, Hui-Yu, Yang, Shun-Fa, Hsiao, Pei-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047044/
https://www.ncbi.nlm.nih.gov/pubmed/24901249
http://dx.doi.org/10.1371/journal.pone.0098943