Cargando…

Multiple Mineralocorticoid Response Elements Localized in Different Introns Regulate Intermediate Conductance K(+) (Kcnn4) Channel Expression in the Rat Distal Colon

An elevated plasma aldosterone and an increased expression of the intermediate conductance K(+) (IK/Kcnn4) channels are linked in colon. This observation suggests that the expression of Kcnn4 gene is controlled through the action of aldosterone on its cognate receptor (i.e., mineralocorticoid recept...

Descripción completa

Detalles Bibliográficos
Autores principales:	O’Hara, Bryan, de la Rosa, Diego Alvarez, Rajendran, Vazhaikkurichi M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047071/ https://www.ncbi.nlm.nih.gov/pubmed/24901797 http://dx.doi.org/10.1371/journal.pone.0098695

Ejemplares similares

Upregulation of Intermediate-Conductance Ca(2+)-Activated K(+) Channels (KCNN4) in Porcine Coronary Smooth Muscle Requires NADPH Oxidase 5 (NOX5)
por: Gole, Hope K. A., et al.
Publicado: (2014)

Segmental differences in upregulated apical potassium channels in mammalian colon during potassium adaptation
por: Perry, Matthew D., et al.
Publicado: (2016)

KCNN2 polymorphisms and cardiac tachyarrhythmias
por: Yu, Chih-Chieh, et al.
Publicado: (2016)

Calcium-Activated Cl(−) Channel: Insights on the Molecular Identity in Epithelial Tissues
por: Rottgen, Trey S., et al.
Publicado: (2018)

Common Variants in KCNN3 are Associated with Lone Atrial Fibrillation
por: Ellinor, Patrick T., et al.
Publicado: (2010)

A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia
por: Grube, Sabrina, et al.
Publicado: (2011)

Variants in the human potassium channel gene (KCNN3) are associated with migraine in a high risk genetic isolate
por: Cox, Hannah C., et al.
Publicado: (2011)

Association analysis of a highly polymorphic CAG Repeat in the human potassium channel gene KCNN3 and migraine susceptibility
por: Curtain, Robert, et al.
Publicado: (2005)

Relevance of Abnormal KCNN1 Expression and Osmotic Hypersensitivity in Ewing Sarcoma
por: Fuest, Sebastian, et al.
Publicado: (2022)

Dataset of KCNQ1, KCNN4, KATP channel expression and dexamethasone modulation of protein kinase signaling in airway epithelial cells
por: Hynes, Darina, et al.
Publicado: (2019)

Kcnn4 Is a Regulator of Macrophage Multinucleation in Bone Homeostasis and Inflammatory Disease
por: Kang, Heeseog, et al.
Publicado: (2014)

Low expression of KCNN3 may affect drug resistance in ovarian cancer
por: Liu, Xia, et al.
Publicado: (2018)

Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease
por: Vega, Génesis, et al.
Publicado: (2020)

KCNN2 Mutation in Pediatric Tremor Myoclonus Dystonia Syndrome with Electrophysiological Evaluation
por: Lavenstein, Bennett, et al.
Publicado: (2022)

New KCNN4 Variants Associated With Anemia: Stomatocytosis Without Erythrocyte Dehydration
por: Allegrini, B., et al.
Publicado: (2022)

Intermediate Conductances during Deactivation of Heteromultimeric Shaker Potassium Channels
por: Zheng, Jie, et al.
Publicado: (1998)

KCNN4 is a diagnostic and prognostic biomarker that promotes papillary thyroid cancer progression
por: Wen, Jialiang, et al.
Publicado: (2020)

Variant spectrum of PIEZO1 and KCNN4 in Japanese patients with dehydrated hereditary stomatocytosis
por: Nakahara, Erina, et al.
Publicado: (2023)

Transposable elements drive intron gain in diverse eukaryotes
por: Gozashti, Landen, et al.
Publicado: (2022)

Differential regulation of K(Ca)2.1 (KCNN1) K(+) channel expression by histone deacetylases in atrial fibrillation with concomitant heart failure
por: Rahm, Ann‐Kathrin, et al.
Publicado: (2021)

Thermosensitive TRPV Channel Subunits Coassemble into Heteromeric Channels with Intermediate Conductance and Gating Properties
por: Cheng, Wei, et al.
Publicado: (2007)

Intermediate-Conductance-Ca2-Activated K Channel Intermediate-Conductance Calcium-Activated Potassium Channel (IKCa1) is Upregulated and Promotes Cell Proliferation in Cervical Cancer
por: Liu, Ling, et al.
Publicado: (2017)

At the origin of spliceosomal introns: Is multiplication of introner-like elements the main mechanism of intron gain in fungi?
por: Collemare, Jérôme, et al.
Publicado: (2013)

Kcnn2 blockade reverses learning deficits in the mouse model of Fetal Alcohol Spectrum Disorders
por: Mohammad, Shahid, et al.
Publicado: (2020)

KCNN4 Promotes the Stemness Potentials of Liver Cancer Stem Cells by Enhancing Glucose Metabolism
por: Fan, Jing, et al.
Publicado: (2022)

Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking
por: Juanes, Rita Cervera, et al.
Publicado: (2023)

Cross-species epigenetic regulation of nucleus accumbens KCNN3 transcripts by excessive ethanol drinking
por: Mulholland, Patrick J., et al.
Publicado: (2023)

Bioinformatics identification and pharmacological validation of Kcnn3/K(Ca)2 channels as a mediator of negative affective behaviors and excessive alcohol drinking in mice
por: Padula, Audrey E., et al.
Publicado: (2020)

Diagnosing dehydrated hereditary stomatocytosis due to a KCNN4 Gardos channel mutation: understanding challenges through study of a multi‐generational family
por: Waldstein, Sasha, et al.
Publicado: (2021)

Mineralocorticoid hypertension
por: Gupta, Vishal
Publicado: (2011)

Expression of genes encoding mineralocorticoid biosynthetic enzymes and the mineralocorticoid receptor, and levels of mineralocorticoids in the bovine follicle and corpus luteum
por: MUKANGWA, Memory, et al.
Publicado: (2019)

Novel Introner-Like Elements in fungi Are Involved in Parallel Gains of Spliceosomal Introns
por: Collemare, Jérôme, et al.
Publicado: (2015)

PlantIntronDB: a database for plant introns that host functional elements
por: Wang, Weiping, et al.
Publicado: (2023)

High Salt Intake Down-Regulates Colonic Mineralocorticoid Receptors, Epithelial Sodium Channels and 11β-Hydroxysteroid Dehydrogenase Type 2
por: Lienhard, Daniel, et al.
Publicado: (2012)

The mineralocorticoid receptor forms higher order oligomers upon DNA binding
por: Fettweis, Gregory, et al.
Publicado: (2023)

Cysteine Mutagenesis and Computer Modeling of the S6 Region of an Intermediate Conductance IKCa Channel
por: Simoes, Manuel, et al.
Publicado: (2002)

Intermediate introns in nuclear genes of euglenids – are they a distinct type?
por: Milanowski, Rafał, et al.
Publicado: (2016)

Identification of Functionally Distinct Na-HCO(3) Co-Transporters in Colon
por: Barmeyer, Christian, et al.
Publicado: (2013)

Increased Red Cell KCNN4 Activity in Sporadic Hereditary Xerocytosis Associated With Enhanced Single Channel Pressure Sensitivity of PIEZO1 Mutant V598M
por: Gnanasambandam, Radhakrishnan, et al.
Publicado: (2018)

Membrane-delimited Inhibition of Maxi-K Channel Activity by the Intermediate Conductance Ca(2+)-activated K Channel
por: Thompson, Jill, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_eov3gkaj7bv8513r3q7li2dnnv