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KIR2DS4 Promotes HIV-1 Pathogenesis: New Evidence from Analyses of Immunogenetic Data and Natural Killer Cell Function
BACKGROUND: KIR2DS4 gene variants encode full-length and truncated protein products, with only the former serving as membrane-bound receptors to activate natural killer (NK) cells. We have previously shown that full-length KIR2DS4 was associated with relatively high viral load and accelerated hetero...
Autores principales: | Merino, Aimee M., Dugast, Anne-Sophie, Wilson, Craig M., Goepfert, Paul A., Alter, Galit, Kaslow, Richard A., Tang, Jianming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047121/ https://www.ncbi.nlm.nih.gov/pubmed/24901871 http://dx.doi.org/10.1371/journal.pone.0099353 |
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