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Heme Oxygenase-1 Regulates Dendritic Cell Function through Modulation of p38 MAPK-CREB/ATF1 Signaling

Dendritic cells (DCs) are critical for the initiation of immune responses including activation of CD8 T cells. Intracellular reactive oxygen species (ROS) levels influence DC maturation and function. Intracellular heme, a product of catabolism of heme-containing metalloproteins, is a key inducer of...

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Detalles Bibliográficos
Autores principales:	Al-Huseini, Laith M. A., Aw Yeang, Han Xian, Hamdam, Junnat M., Sethu, Swaminathan, Alhumeed, Naif, Wong, Wai, Sathish, Jean G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047411/ https://www.ncbi.nlm.nih.gov/pubmed/24719331 http://dx.doi.org/10.1074/jbc.M113.532069

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