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Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+)
Assessment of the network of toxicity pathways by Omics technologies and bioinformatic data processing paves the road toward a new toxicology for the twenty-first century. Especially, the upstream network of responses, taking place in toxicant-treated cells before a point of no return is reached, is...
Autores principales: | Krug, A K, Gutbier, S, Zhao, L, Pöltl, D, Kullmann, C, Ivanova, V, Förster, S, Jagtap, S, Meiser, J, Leparc, G, Schildknecht, S, Adam, M, Hiller, K, Farhan, H, Brunner, T, Hartung, T, Sachinidis, A, Leist, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047858/ https://www.ncbi.nlm.nih.gov/pubmed/24810058 http://dx.doi.org/10.1038/cddis.2014.166 |
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