The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer

The survival of prostate cancer (PrCa) patients is associated with the transition to hormone-independent tumor growth and metastasis. Clinically, the dysregulation of androgen action has been associated with the formation of PrCa and the outcome of androgen deprivation therapy in PrCa. CCAAT/enhance...

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Detalles Bibliográficos
Autores principales: Chuang, C-H, Wang, W-J, Li, C-F, Ko, C-Y, Chou, Y-H, Chuu, C-P, Cheng, T-L, Wang, J-M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047860/
https://www.ncbi.nlm.nih.gov/pubmed/24810056
http://dx.doi.org/10.1038/cddis.2014.106

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