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Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy
Intestinal epithelial cells (IECs) not only have a critical function in the absorption of nutrients, but also act as a physical barrier between our body and the outside world. Damage and death of the epithelial cells lead to the breakdown of this barrier function and inflammation due to access of th...
Autores principales: | Grabinger, T, Luks, L, Kostadinova, F, Zimberlin, C, Medema, J P, Leist, M, Brunner, T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047863/ https://www.ncbi.nlm.nih.gov/pubmed/24832600 http://dx.doi.org/10.1038/cddis.2014.183 |
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