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Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors

Hereditary retinal degeneration (RD) relates to a heterogeneous group of blinding human diseases in which the light sensitive neurons of the retina, the photoreceptors, die. RD is currently untreatable and the underlying cellular mechanisms remain poorly understood. However, the activity of the enzy...

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Detalles Bibliográficos
Autores principales:	Sahaboglu, A, Tanimoto, N, Bolz, S, Garrido, M G, Ueffing, M, Seeliger, M W, Löwenheim, H, Ekström, P, Paquet-Durand, F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047865/ https://www.ncbi.nlm.nih.gov/pubmed/24853412 http://dx.doi.org/10.1038/cddis.2014.208

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