Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression

Estrogen receptor-alpha positive (ER(+)) breast cancers comprise the majority of human breast cancers, but molecular mechanisms underlying this subtype of breast cancers remain poorly understood. Here, we show that ER(+) mammary luminal tumors arising in Tip30(−/−)MMTV-Neu mice exhibited increased e...

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Detalles Bibliográficos
Autores principales: Chen, F, Li, A, Gao, S, Hollern, D, Williams, M, Liu, F, VanSickle, E A, Andrechek, E, Zhang, C, Yang, C, Luo, R, Xiao, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047867/
https://www.ncbi.nlm.nih.gov/pubmed/24853420
http://dx.doi.org/10.1038/cddis.2014.224

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