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Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H(2)O(2)
It is commonly recognized that diabetic complications involve increased oxidative stress directly triggered by hyperglycemia. The most important cellular protective systems against such oxidative stress have yet remained unclear. Here we show that the selenoprotein thioredoxin reductase 1 (TrxR1), e...
Autores principales: | Peng, X, Mandal, P K, Kaminskyy, V O, Lindqvist, A, Conrad, M, Arnér, E S J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047868/ https://www.ncbi.nlm.nih.gov/pubmed/24853413 http://dx.doi.org/10.1038/cddis.2014.209 |
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