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Pigment epithelium-derived factor expression prolongs survival and enhances the cytotoxicity of low-dose chemotherapy in castration-refractory prostate cancer
There is currently no cure for advanced castration-refractory prostate cancer (CRPC) despite the recent approval of several new therapeutic agents. We report here the anti-tumor effect of the angio-inhibitory pigment epithelium-derived factor (PEDF) in the metastatic LNCaP-derivative CRPC CL1 model...
Autores principales: | Nelius, T, Martinez-Marin, D, Hirsch, J, Miller, B, Rinard, K, Lopez, J, de Riese, W, Filleur, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047872/ https://www.ncbi.nlm.nih.gov/pubmed/24810046 http://dx.doi.org/10.1038/cddis.2014.180 |
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