Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice

Rasfonin is a novel 2-pyrone derivative reported to induce apoptosis in ras-dependent cells. In this study, its effects on ras-mutated pancreatic cancer cells were investigated in vitro and in vivo. Two human pancreatic cancer cell lines Panc-1 (mutated K-ras) and BxPC-3 (wild-type K-ras) were selec...

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Detalles Bibliográficos
Autores principales: Xiao, Z, Li, L, Li, Y, Zhou, W, Cheng, J, Liu, F, Zheng, P, Zhang, Y, Che, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047882/
https://www.ncbi.nlm.nih.gov/pubmed/24853419
http://dx.doi.org/10.1038/cddis.2014.213

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