Mammalian STE20-like kinase 2, not kinase 1, mediates photoreceptor cell death during retinal detachment

Photoreceptor cell death is the definitive cause of vision loss in retinal detachment (RD). Mammalian STE20-like kinase (MST) is a master regulator of both cell death and proliferation and a critical factor in development and tumorigenesis. However, to date the role of MST in neurodegeneration has n...

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Detalles Bibliográficos
Autores principales: Matsumoto, H, Murakami, Y, Kataoka, K, Lin, H, Connor, K M, Miller, J W, Zhou, D, Avruch, J, Vavvas, D G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047884/
https://www.ncbi.nlm.nih.gov/pubmed/24874741
http://dx.doi.org/10.1038/cddis.2014.218

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