β-Lapachone induces programmed necrosis through the RIP1-PARP-AIF-dependent pathway in human hepatocellular carcinoma SK-Hep1 cells

β-Lapachone activates multiple cell death mechanisms including apoptosis, autophagy and necrotic cell death in cancer cells. In this study, we investigated β-lapachone-induced cell death and the underlying mechanisms in human hepatocellular carcinoma SK-Hep1 cells. β-Lapachone markedly induced cell...

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Detalles Bibliográficos
Autores principales: Park, E J, Min, K-j, Lee, T-J, Yoo, Y H, Kim, Y-S, Kwon, T K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047891/
https://www.ncbi.nlm.nih.gov/pubmed/24832602
http://dx.doi.org/10.1038/cddis.2014.202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047891/
https://www.ncbi.nlm.nih.gov/pubmed/24832602
http://dx.doi.org/10.1038/cddis.2014.202

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