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The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa
Retinitis pigmentosa (RP) is a group of inherited diseases that cause blindness due to the progressive death of rod and cone photoreceptors in the retina. There are currently no effective treatments for RP. Inherited mutations in rhodopsin, the light-sensing protein of rod photoreceptor cells, are t...
Autores principales: | Parfitt, D A, Aguila, M, McCulley, C H, Bevilacqua, D, Mendes, H F, Athanasiou, D, Novoselov, S S, Kanuga, N, Munro, P M, Coffey, P J, Kalmar, B, Greensmith, L, Cheetham, M E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047904/ https://www.ncbi.nlm.nih.gov/pubmed/24853414 http://dx.doi.org/10.1038/cddis.2014.214 |
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