Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer

The involvement of Axl kinase in non-small cell lung cancer's (NSCLC) acquired resistance to tyrosine kinase inhibitors (TKIs) gefitinib or erlotinib has been identified recently, but the mechanism by which Axl contributes to TKI resistance is largely unknown. MicroRNAs (miRNAs) repress gene ex...

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Detalles Bibliográficos
Autores principales: Wang, Y, Xia, H, Zhuang, Z, Miao, L, Chen, X, Cai, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047906/
https://www.ncbi.nlm.nih.gov/pubmed/24832599
http://dx.doi.org/10.1038/cddis.2014.186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047906/
https://www.ncbi.nlm.nih.gov/pubmed/24832599
http://dx.doi.org/10.1038/cddis.2014.186

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