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Simultaneous loss of phospholipase Cδ1 and phospholipase Cδ3 causes cardiomyocyte apoptosis and cardiomyopathy

Phospholipase C (PLC) is a key enzyme in phosphoinositide turnover. Among 13 PLC isozymes, PLCδ1 and PLCδ3 share high sequence homology and similar tissue distribution, and are expected to have functional redundancy in many tissues. We previously reported that the simultaneous loss of PLCδ1 and PLCδ...

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Detalles Bibliográficos
Autores principales:	Nakamura, Y, Kanemaru, K, Kojima, R, Hashimoto, Y, Marunouchi, T, Oka, N, Ogura, T, Tanonaka, K, Fukami, K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047916/ https://www.ncbi.nlm.nih.gov/pubmed/24810051 http://dx.doi.org/10.1038/cddis.2014.181

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