P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression

Recently, a novel class of transcripts, long non-coding RNAs (lncRNAs), is being identified at a rapid pace. These RNAs have critical roles in diverse biological processes, including tumorigenesis. Here we report that taurine-upregulated gene 1 (TUG1), a 7.1-kb lncRNA, recruiting and binding to poly...

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Detalles Bibliográficos
Autores principales: Zhang, E-b, Yin, D-d, Sun, M, Kong, R, Liu, X-h, You, L-h, Han, L, Xia, R, Wang, K-m, Yang, J-s, De, W, Shu, Y-q, Wang, Z-x
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047917/
https://www.ncbi.nlm.nih.gov/pubmed/24853421
http://dx.doi.org/10.1038/cddis.2014.201

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