Cargando…

ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS

The Rho/ROCK/LIMK pathway is central for the mediation of repulsive environmental signals in the central nervous system. Several studies using pharmacological Rho-associated protein kinase (ROCK) inhibitors have shown positive effects on neurite regeneration and suggest additional pro-survival effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Koch, J C, Tönges, L, Barski, E, Michel, U, Bähr, M, Lingor, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047920/
https://www.ncbi.nlm.nih.gov/pubmed/24832597
http://dx.doi.org/10.1038/cddis.2014.191