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ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS
The Rho/ROCK/LIMK pathway is central for the mediation of repulsive environmental signals in the central nervous system. Several studies using pharmacological Rho-associated protein kinase (ROCK) inhibitors have shown positive effects on neurite regeneration and suggest additional pro-survival effec...
Autores principales: | Koch, J C, Tönges, L, Barski, E, Michel, U, Bähr, M, Lingor, P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047920/ https://www.ncbi.nlm.nih.gov/pubmed/24832597 http://dx.doi.org/10.1038/cddis.2014.191 |
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