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Wnt inhibitory factor 1 suppresses cancer stemness and induces cellular senescence

Hyperactivation of the Wingless-type (Wnt)/β-catenin pathway promotes tumor initiation, tumor growth and metastasis in various tissues. Although there is evidence for the involvement of Wnt/β-catenin pathway activation in salivary gland tumors, the precise mechanisms are unknown. Here we report for...

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Detalles Bibliográficos
Autores principales: Ramachandran, I, Ganapathy, V, Gillies, E, Fonseca, I, Sureban, S M, Houchen, C W, Reis, A, Queimado, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047921/
https://www.ncbi.nlm.nih.gov/pubmed/24853424
http://dx.doi.org/10.1038/cddis.2014.219