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Uridine 5′-Triphosphate Promotes In Vitro Schwannoma Cell Migration through Matrix Metalloproteinase-2 Activation
In response to peripheral nerve injury, Schwann cells adopt a migratory phenotype and modify the extracellular matrix to make it permissive for cell migration and axonal re-growth. Uridine 5′-triphosphate (UTP) and other nucleotides are released during nerve injury and activate purinergic receptors...
Autores principales: | Lamarca, Aloa, Gella, Alejandro, Martiañez, Tania, Segura, Mònica, Figueiro-Silva, Joana, Grijota-Martinez, Carmen, Trullas, Ramón, Casals, Núria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048211/ https://www.ncbi.nlm.nih.gov/pubmed/24905332 http://dx.doi.org/10.1371/journal.pone.0098998 |
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