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Exploring the Electron Transfer Pathway in the Oxidation of Avermectin by CYP107Z13 in Streptomyces ahygroscopicus ZB01

Streptomyces ahygroscopicus ZB01 can effectively oxidize 4″-OH of avermectin to form 4″-oxo-avermectin. CYP107Z13 is responsible for this site-specific oxidation in ZB01. In the present study, we explored the electron transfer pathway in oxidation of avermectin by CYP107Z13 in ZB01. A putative [3Fe-...

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Detalles Bibliográficos
Autores principales: Li, Mei, Zhang, Yujie, Zhang, Lin, Yang, Xiaoyan, Jiang, Xiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048220/
https://www.ncbi.nlm.nih.gov/pubmed/24905717
http://dx.doi.org/10.1371/journal.pone.0098916