Automated Assessment of β-Cell Area and Density per Islet and Patient Using TMEM27 and BACE2 Immunofluorescence Staining in Human Pancreatic β-Cells

In this study we aimed to establish an unbiased automatic quantification pipeline to assess islet specific features such as β-cell area and density per islet based on immunofluorescence stainings. To determine these parameters, the in vivo protein expression levels of TMEM27 and BACE2 in pancreatic...

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Detalles Bibliográficos
Autores principales: Rechsteiner, Markus P., Floros, Xenofon, Boehm, Bernhard O., Marselli, Lorella, Marchetti, Piero, Stoffel, Markus, Moch, Holger, Spinas, Giatgen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048234/
https://www.ncbi.nlm.nih.gov/pubmed/24905913
http://dx.doi.org/10.1371/journal.pone.0098932

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