ZO-1 and ZO-2 Are Required for Extra-Embryonic Endoderm Integrity, Primitive Ectoderm Survival and Normal Cavitation in Embryoid Bodies Derived from Mouse Embryonic Stem Cells

The Zonula Occludens proteins ZO-1 and ZO-2 are cell-cell junction-associated adaptor proteins that are essential for the structural and regulatory functions of tight junctions in epithelial cells and their absence leads to early embryonic lethality in mouse models. Here, we use the embryoid body, a...

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Detalles Bibliográficos
Autores principales: Phua, Dominic C. Y., Xu, Jianliang, Ali, Safiah Mohamed, Boey, Adrian, Gounko, Natalia V., Hunziker, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048262/
https://www.ncbi.nlm.nih.gov/pubmed/24905925
http://dx.doi.org/10.1371/journal.pone.0099532

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