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Clonal Analysis of the T-Cell Response to In Vivo Expressed Mycobacterium tuberculosis Protein Rv2034, Using a CD154 Expression Based T-Cell Cloning Method
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of death worldwide. A better understanding of the role of CD4(+) and CD8(+) T cells, which are both important to TB protection, is essential to unravel the mechanisms of protection and to identify the key antigens...
Autores principales: | Commandeur, Susanna, Coppola, Mariateresa, Dijkman, Karin, Friggen, Annemieke H., van Meijgaarden, Krista E., van den Eeden, Susan J. F., Wilson, Louis, van der Ploeg-van Schip, Jolien J., Franken, Kees L. M. C., Geluk, Annemieke, Ottenhoff, Tom H. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048274/ https://www.ncbi.nlm.nih.gov/pubmed/24905579 http://dx.doi.org/10.1371/journal.pone.0099203 |
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